Regulatory T cells (Tregs) are crucial for the maintenance of immunologic tolerance to self and foreign antigen. Additionally, they prevent immunopathology after infection resolution by down regulating immune response. Their immunosuppressive abilities are attributed to their production of inhibitory cytokines such as interleukin 10 and transforming growth factor β. Cells are sourced from healthy donors from world-renowned blood institutions using Institutional Review Board (IRB)-approved consent forms and protocols. Donors are screened for HIV-1, HIV-2, hepatitis B, hepatitis C, human T-lymphotropic virus, syphilis, Chagas and West Nile virus.

Source: Peripheral Blood

Donor Status: Normal

Isolation Method: Positive Immunomagnetic Selection

Format: Frozen in CryoStor® CS10, shipped in dry ice

Purity: ≥ 95% by flow cytometry

Viability: ≥ 95% by flow cytometry

Anticoagulant: Acid-citrate-dextrose solution A (ACDA)

Donor details: Refer to the lot-specific Certificate of Analysis (Included with product shipment)

NOTE: The certificate of analysis is mailed with all orders. An electronic version of the certificate of analysis is available upon request by emailing info@axelabio.com. Please provide the product catalog number and lot number in the request.